4-Hydroxybenzaldehyde
Synonyms: 4-hydroxy-benzaldehyd;4-hydroxybenzaldehyde,p-formylphenol,4-formylphenol;4-Hydroxybenzenecarbonal;Benzaldehyde, p-hydroxy-;benzaldehyde,-hydroxy-;p-Formylphenol;p-hydroxy-benzaldehyd;p-Hydroxybenzaldlehyde
CAS: 123-08-0
MF: C7H6O2
MW: 122.12
EINECS: 204-599-1
Melting point 112-116 °C(lit.)
Boiling point 191°C 50mm
density 1,129 g/cm3
FEMA 3984
Fp 174°C
storage temp. Store at 2-8°C
color light yellow to light brown
Water Solubility 13 g/L (30 oC)
Sensitive Air Sensitive
Merck 14,4811
Chemical Properties It is colorless crystalline powder. Melting point: 115-116 ℃, the relative density is 1.129 (30/4 ℃). In the air, it is easily to be sublimated. It is easily soluble in alcohol, ether, acetone, and ethyl acetate, slightly soluble in water (at 30.5 ℃, its water solubility is 1.38g/100ml); it can also be dissolved in benzene (at 65 ℃, its solubility in benzene is 3.68g/ml). It has aromatic odor.
Uses 1. It can be used for the synthesis of organic compounds and medicine.
2. The good is also the intermediate of the pharmaceutical, perfume, and liquid crystal. p-Hydroxybenzaldehyde can be used for the production of TMP (trimethoprim), amoxicillin, cefadroxil cephalosporins, artificial gastrodin, farrerol, bezafibrate, and esmolol; it can also be used for the production of perfume anisaldehyde, vanillin, ethyl vanillin, and raspberry ketone.
3. It is the key raw material for the production of p-hydroxy phenylglycine (p-hydroxy phenylglycine is the key intermediate of the new generation of semi-synthetic penicillin amoxicillin). It is also the key intermediate raw material of the production of pesticides-bromoxynil.
4. p-Hydroxybenzaldehyde is an important intermediate of the pharmaceutical industry and the perfume industry.
5. It is an important intermediate of medicine, perfume, and pesticides for the synthesis of drugs like hydroxyl ampicillin, trimethoprim, and 3-methoxy benzaldehyde. It can also used for synthesizing polymers and producing pharmaceutical raw materials.